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BMS_Oxford fellowship in Matrix Biology

 

 


Publications:

 

Akasaka E, Kleiser S, Sengle G, Bruckner-Tuderman L, Nyström A. Diversity of Mechanisms Underlying Latent TGF-β Activation in Recessive Dystrophic Epidermolysis Bullosa. J Invest Dermatol. 2020 Dec 14:S0022-202X(20)32357-5. doi: 10.1016/j.jid.2020.10.024.

 

Auler M, Bergmeier V, Georgieva VS, Pitzler L, Frie C, Nüchel J, Eckes B, Hinz B, Brachvogel B. miR-127-3p is an epigenetic activator of myofibroblast senescence situated within the miRNA enriched Dlk1-Dio3 imprinted domain on mouse chromosome 12. J Invest Dermatol. 2020 Dec 3:S0022-202X(20)32356-3. doi: 10.1016/j.jid.2020.11.011. 

Costa B, Fletcher MNC, Boskovic P, Ivanova EL, Eisemann T, Lohr S, Bunse L, Löwer M, Burchard S, Korshunov A, Coltella N, Cusimano M, Naldini L, Liu HK, Platten M, Radlwimmer B, Angel P, Peterziel H. A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors. Cancers (Basel). 2021 Jan 10;13(2):E230. doi: 10.3390/cancers13020230.

 

Dreiner M, Willwacher S, Kramer A, Kümmel J, Frett T, Zaucke F, Liphardt AM, Gruber M, Niehoff A. Short-term Response of Serum Cartilage Oligomeric Matrix Protein to Different Types of Impact Loading Under Normal and Artificial Gravity. Front Physiol. 2020 Aug 31;11:1032. doi: 10.3389/fphys.2020.01032.

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Grolman JM, Weinand P, Mooney DJ. Extracellular matrix plasticity as a driver of cell spreading. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):25999-26007. doi: 10.1073/pnas.2008801117.

 

Guo SS, Au TYK, Wynn S, Aszodi A, Chan D, Fässler R, Cheah KSE. β1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs. Development. 2020 Nov 18;147(22):dev192724. doi: 10.1242/dev.192724.

 

Imhof T, Korkmaz Y, Koch M, Sengle G, Schiavinato A. EMILIN proteins are novel extracellular constituents of the dentin-pulp complex. Sci Rep. 2020 Sep 18;10(1):15320. doi: 10.1038/s41598-020-72123-2.

 

Imhof T, Rosenblatt K, Pryymachuk G, Weiland D, Noetzel N, Deschner J, Baris OR, Kimoloi S, Koch M, Wiesner RJ, Korkmaz Y. Epithelial loss of mitochondrial oxidative phosphorylation leads to disturbed enamel and impaired dentin matrix formation in postnatal developed mouse incisor. Sci Rep. 2020 Dec 16;10(1):22037. doi: 10.1038/s41598-020-77954-7.

 

Kim CS, Ding X, Allmeroth K, Biggs LC, Kolenc OI, L'Hoest N, Chacón-Martínez CA, Edlich-Muth C, Giavalisco P, Quinn KP, Denzel MS, Eming SA, Wickström SA. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle. Cell Metab. 2020 Oct 6;32(4):629-642.e8. doi: 10.1016/j.cmet.2020.08.011.

 

Kouwenberg M, Rops A, Bakker-van Bebber M, Diepeveen L, Götte M, Hilbrands L, van der Vlag J. Role of syndecan-1 in the interaction between dendritic cells and T cells. PLoS One. 2020 Jul 23;15(7):e0230835. doi: 10.1371/journal.pone.0230835.

 

Kreuser U, Buchert J, Haase A, Richter W, Diederichs S. Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Cells. Front Cell Dev Biol. 2020 Oct 30;8:581331. doi: 10.3389/fcell.2020.581331.

 

Kuehn J, Espinoza-Sanchez NA, Teixeira FCOB, Pavão MSG, Kiesel L, Győrffy B, Greve B, Götte M. Prognostic significance of hedgehog signaling network-related gene expression in breast cancer patients. J Cell Biochem. 2021 Jan 8. doi: 10.1002/jcb.29886.

 

Li L, Song J, Chuquisana O, Hannocks MJ, Loismann S, Vogl T, Roth J, Hallmann R, Sorokin L. Endothelial Basement Membrane Laminins as an Environmental Cue in Monocyte Differentiation to Macrophages. Front Immunol. 2020 Oct 30;11:584229. doi: 10.3389/fimmu.2020.584229.

 

Li S, Stöckl S, Lukas C, Götz J, Herrmann M, Federlin M, Grässel S. hBMSC-Derived Extracellular Vesicles Attenuate IL-1β-Induced Catabolic Effects on OA-Chondrocytes by Regulating Pro-inflammatory Signaling Pathways. Front Bioeng Biotechnol. 2020 Dec 14;8:603598. doi: 10.3389/fbioe.2020.603598.

 

Lorenzen I, Eble JA, Hanschmann EM. Thiol switches in membrane proteins - Extracellular redox regulation in cell biology. Biol Chem. 2020 Oct 28:/j/bchm.ahead-of-print/hsz-2020-0266/hsz-2020-0266.xml. doi: 10.1515/hsz-2020-0266.

 

Melnik S, Gabler J, Dreher SI, Hecht N, Hofmann N, Großner T, Richter W. MiR-218 affects hypertrophic differentiation of human mesenchymal stromal cells during chondrogenesis via targeting RUNX2, MEF2C, and COL10A1. Stem Cell Res Ther. 2020 Dec 10;11(1):532. doi: 10.1186/s13287-020-02026-6.

 

Mohamed HT, Untereiner V, Cinque G, Ibrahim SA,Infrared Microspectroscopy and Imaging Analysis of Inflammatory and Non-Inflammatory Breast Cancer Cells and Their GAG Secretome. Götte M, Nguyen NQ, Rivet R, Sockalingum GD, Brézillon S. Molecules. 2020 Sep 19;25(18):4300. doi: 10.3390/molecules25184300.

 

Niedermair T, Lukas C, Li S, Stöckl S, Craiovan B, Brochhausen C, Federlin M, Herrmann M, Grässel S. Influence of Extracellular Vesicles Isolated From Osteoblasts of Patients With Cox-Arthrosis and/or Osteoporosis on Metabolism and Osteogenic Differentiation of BMSCs. Front Bioeng Biotechnol. 2020 Dec 23;8:615520. doi: 10.3389/fbioe.2020.615520.

 

Niland S, Eble JA. Hold on or Cut? Integrin- and MMP-Mediated Cell-Matrix Interactions in the Tumor Microenvironment. Int J Mol Sci. 2020 Dec 28;22(1):238. doi: 10.3390/ijms22010238.

 

Ponandai-Srinivasan S, Saare M, Boggavarapu NR, Frisendahl C, Ehrström S, Riethmüller C, García-Uribe PA, Rettkowski J, Iyengar A, Salumets A, Lalitkumar PGL, Götte M, Gemzell-Danielsson K. Syndecan-1 modulates the invasive potential of endometrioma via TGF-β signalling in a subgroup of women with endometriosis. Hum Reprod. 2020 Oct 1;35(10):2280-2293. doi: 10.1093/humrep/deaa164.

 

Rellmann Y, Eidhof E, Dreier R. ER stress-induced cell death in osteoarthritic cartilage. Cell Signal. 2021 Feb;78:109880. doi: 10.1016/j.cellsig.2020.109880.

 

Reuten R, Zendehroud S, Nicolau M, Fleischhauer L, Laitala A, Kiderlen S, Nikodemus D, Wullkopf L, Nielsen SR, McNeilly S, Prein C, Rafaeva M, Schoof EM, Furtwängler B, Porse BT, Kim H, Won KJ, Sudhop S, Zornhagen KW, Suhr F, Maniati E, Pearce OMT, Koch M, Oddershede LB, Van Agtmael T, Madsen CD, Mayorca-Guiliani AE, Bloch W, Netz RR, Clausen-Schaumann H, Erler JT. Basement membrane stiffness determines metastases formation. Nat Mater. 2021 Jan 25. doi: 10.1038/s41563-020-00894-0.

 

Stöckl S, Lindner G, Li S, Schuster P, Haferkamp S, Wagner F, Prodinger PM, Multhoff G, Boxberg M, Hillmann A, Bauer RJ, Grässel S. SOX9 Knockout Induces Polyploidy and Changes Sensitivity to Tumor Treatment Strategies in a Chondrosarcoma Cell Line. Int J Mol Sci. 2020 Oct 15;21(20):7627. doi: 10.3390/ijms21207627.

 

Timmen M, Hidding H, Götte M, Khassawna TE, Kronenberg D, Stange R. The heparan sulfate proteoglycan Syndecan-1 influences local bone cell communication via the RANKL/OPG axis. Sci Rep. 2020 Nov 25;10(1):20510. doi: 10.1038/s41598-020-77510-3.

 

van Dijk FS, Semler O, Etich J, Köhler A, Jimenez-Estrada JA, Bravenboer N, Claeys L, Riesebos E, Gegic S, Piersma SR, Jimenez CR, Waisfisz Q, Flores CL, Nevado J, Harsevoort AJ, Janus GJM, Franken AAM, van der Sar AM, Meijers-Heijboer H, Heath KE, Lapunzina P, Nikkels PGJ, Santen GWE, Nüchel J, Plomann M, Wagener R, Rehberg M, Hoyer-Kuhn H, Eekhoff EMW, Pals G, Mörgelin M, Newstead S, W Interaction between KDELR2 and HSP47 as a Key Determinant in Osteogenesis Imperfecta Caused by Bi-allelic Variants in KDELR2.ilson BT, Ruiz-Perez VL, Maugeri A, Netzer C, Zaucke F, Micha D. Am J Hum Genet. 2020 Nov 5;107(5):989-999. doi: 10.1016/j.ajhg.2020.09.009.

 

Westermann LM, Fleischhauer L, Vogel J, Jenei-Lanzl Z, Ludwig NF, Schau L, Morellini F, Baranowsky A, Yorgan TA, Di Lorenzo G, Schweizer M, de Souza Pinheiro B, Guarany NR, Sperb-Ludwig F, Visioli F, Oliveira Silva T, Soul J, Hendrickx G, Wiegert JS, Schwartz IVD, Clausen-Schaumann H, Zaucke F, Schinke T, Pohl S, Danyukova T. Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma. Dis Model Mech. 2020 Nov 18;13(11):dmm046425. doi: 10.1242/dmm.046425.

 

Zbinden A, Carvajal Berrio DA, Urbanczyk M, Layland SL, Bosch M, Fliri S, Lu CE, Jeyagaran A, Loskill P, Duffy GP, Schenke-Layland K. Fluorescence lifetime metabolic mapping of hypoxia-induced damage in pancreatic pseudo-islets. J Biophotonics. 2020 Dec;13(12):e202000375. doi: 10.1002/jbio.202000375.

 

Zbinden A, Layland SL, Urbanczyk M, Carvajal Berrio DA, Marzi J, Zauner M, Hammerschmidt A, Brauchle EM, Sudrow K, Fink S, Templin M, Liebscher S, Klein G, Deb A, Duffy GP, Crooks GM, Eble JA, Mikkola HKA, Nsair A, Seifert M, Schenke-Layland K. Nidogen‐1 Mitigates Ischemia and Promotes Tissue Survival and Regeneration. Adv. Sci. 2020. doi: 10.1002/advs.202002500

 

Zbinden A, Urbanczyk M, Layland SL, Becker L, Marzi J, Bosch M, Loskill P, Duffy GP, Schenke-Layland K. Collagen and Endothelial Cell Coculture Improves β-Cell Functionality and Rescues Pancreatic Extracellular Matrix. Tissue Eng Part A. 2020 Nov 6. doi: 10.1089/ten.TEA.2020.0250.

 

 

 


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